Antihistamines in cough and cold remedies.Įmergency medical services should be sought immediately when an overdose is suspected or if signs appear.Selective serotonin reuptake inhibitors (SSRIs) for depression.

Monoamine oxidase inhibitors (MAOIs) for depression.

Other Polydrug Interactions with Overdose Potential When used with opioids or opiates such as methadone, Ox圜ontin, etc., Valium increases the toxic effects of those drugs upon the central nervous system.Ĭoncurrently abusing these substances with Valium could decrease the threshold at which the inherent dangers of the opiate/opioid drug are experienced-even if a person has previously exhibited a tolerance for these drugs on their own.

They have similar sedative and depressant effects and are misguidedly used to enhance the effects of the other.Īlcohol consumption, however, can impede the metabolism of Valium causing elevated amounts to remain in the system as alcohol is consumed. Alcohol with ValiumĪlcohol with Valium is a frequently abused combination that can lead to overdose. The following are examples of adverse interactions and is not intended to be an all-inclusive list. There are also other prescription drugs, illegal drugs, over-the-counter medications and herbal supplements that cause overdose when used with Valium. When combined with Valium, all sedating drugs such as alcohol, opioids, and other benzodiazepines can produce severe and prolonged respiratory distress and heart problems. Polydrug use greatly complicates the effects of Valium and contributes significantly to overdose involving Valium. Polydrug use is the number one cause of all overdose fatalities.

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